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Rating one of the best vitamin B12 dietary supplements of 2022

Vitamin B12 is an important nutrient that’s tough to get in massive quantities in lots of meals sources, particularly if you’re a vegetarian or a vegan.

It features nearly like a hormone, and performs a job in an enormous variety of bodily features important for well being.

For those who aren’t positive how a lot vitamin B12 you want and the place you must get it from, we’ve acquired you coated.

Our researchers dug into the scientific analysis to scout out one of the best vitamin B12 dietary supplements and ranked them. On prime of that, we’ve gone in-depth on the science of B12 supplementation.

Why You Ought to Belief Us

    Our advisory panel and our analysis workforce rank one of the best well being merchandise and dietary supplements primarily based on efficiency, label accuracy, and the efficacy of the components within the merchandise.


Final up to date: August 31, 2022
B12 dietary supplements thought of: 21
Hours of analysis: 43
Specialists reviewed: 9
Scientific papers referenced: 17


Greatest Total

  • One of the potent B12 dietary supplements available on the market
  • Vegan-friendly, tastes nice, and straightforward to make use of
  • 5000 mcg per serving
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Greatest for anxiousness

TL VitaminBComplex 2000x

2. Clear Labs Vitamin B-Complicated

  • Comprises your entire vary of b-vitamins together with co-vitamins like choline, inositol and vitamin C
  • Helps keep a steady temper
  • Greatest B12 vitamin for Seniors
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Greatest for power


  • Fast under-the-tongue B12 supply mechanism
  • Has an energy-boosting properties of vitamin B12 for elevating your alertness and power ranges earlier than a exercise
  • Potent temper, mind and metabolism booster
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nature made b12

4. Nature Made B12 Timed Launch

  • Breaks down and transforms meals into power to maintain you going all day
  • It’s a Gluten-free with no added preservatives and no synthetic favors
  • Has a time-release formulation that promotes prolonged vitamin absorption within the physique
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vegansafe b12
  • It’s liquid-form that makes it uber-potent with a light-weight and candy taste to it
  • Might help with fatigue and low power to gas your physique for extra power the entire day
  • Has constructive results on sleep and helps normalize our physique clock
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71MPiHMd4AL. SX522

6. Backyard of Life Vitamin Code B12

  • It supplies help for digestion, metabolism, and anemia
  • Helps keep wholesome purple blood cells and wholesome nerves
  • Offers vitamins which are from a variety of fruits, greens and its pure extracts
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617jaFHy8gL. SX522

7. Bronson Vitamin Sustained Launch B12

  • Gradual launch kind to supply steadiness stream of vitamin B12
  • Helps in power producton and in addition in mind and nervous system
  • Makes use of the very best high quality of components and is Non-GMO
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zenwise b12

8. Zenwise Well being Vitamin B12

  • Helps to supply enegry increase all day lengthy
  • Offers a robust however not outrageously excessive dosage
  • Helps to guide an energetic and energetic life-style at any age
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61L5KiLMFLL. AC SL1200
  • The epitome of a excessive dosage, fast-delivery possibility
  • Contained in fast-dissolve tablets that may quickly elevate your physique’s circulating ranges of vitamin B12
  • Simple to take with out water and is 100% vegetarian
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jarrow b12

10. Jarrow Formulation Methylcobalamin

  • Provides its vitamin B12 in an artificially-sweetened chewable lozenge kind
  • Maintains and helps mind and nerve well being and sleep and wake cycles
  • It’s Gluten free and free from all widespread allergens
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11. SBR Vitamin Vitamin B12 Drops

  • Will increase metabolism and improves digestion
  • Improves psychological readability and lifts mind fog
  • Simpler to devour
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1. Stay Aware B12


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For individuals who’re critical about taking essentially the most potent B12 complement available on the market, Stay Aware B12 doesn’t fiddle.

Stay Aware B12 supplies one of the potent B12 dietary supplements available on the market at 5000 mcg per serving. It’s designed for use sublingually and incorporates essentially the most bioavailable type of B12, methylcobalamin. This ensures that extra of the B12 will get to go the place it must. It’s manufactured within the USA, beneath string GMP tips.

It’s additionally freed from soy, gluten, shellfish, dairy, and GMO’s. Stay Aware goes the additional mile by offering third-party testing to make sure the purity and high quality of its B12 complement.

For those who’re going to take a B12 complement for power, reminiscence, and immune system perform, Stay Aware B12 is your best option.

BodyNutrition‘s total #1-rated B12 winner of 2022.

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2. Twinlab B12 Dots

twinlab b dots

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TwinLabs B12 dots are nice if you happen to can’t stand swallowing capsules, or if you would like a speedy supply of your B12 dosage.

Every 500 mcg dot quickly dissolves when positioned beneath your tongue, and the B12 is delivered proper to your bloodstream through the mucous tissue within the backside of your mouth.

On condition that these dots scored very extremely on impartial analytical testing for purity and dosage, you’ll be able to ensure that you might be getting the marketed quantity of vitamin B12.

3. Nature Made B12 Timed Launch

nature made b12

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With 1000 mcg of vitamin B12 per serving and a specially-formulated sluggish launch capsule, Nature Made delivers an easy and efficient complement.

It’s been verified for purity and dosage by impartial laboratory testing, and it handed with flying colours. It’s very laborious to go fallacious with this B12 complement.

4. VeganSafe B12

vegansafe b12

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If you need a super-high dose B12 complement that’s been independently examined for purity and focus, VeganSafe B12 ought to be your alternative.

It has no extraneous components and each serving from the dropper bottle has 2500 mcg of vitamin B12.

The one draw back? it’s laborious to persistently measure dosage from a dropper.

5. Backyard of Life Vitamin Code B12

garden of life vitamin code b12

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The vitamin B12 in Backyard of Life Vitamin Code B12 is supplied alongside extracts from a variety of vegatables and fruits.

The first disadvantage is that, as a result of B12 is generally present in dairy and animal merchandise, offering fruit and vegetable extracts might not mirror the “pure setting” through which vitamin B12 is discovered.

6. Bronson Vitamin Sustained Launch B12

Bronson B12

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Bronson’s slow-release B12 is well-suited for long-term use due to its stable 1000 mcg dosage and its slow-release formulation.

Nonetheless, Bronson will get beat out by different dietary supplements which have impartial lab testing of their purity.

7. MaryRuth Methyl B12 Spray

maryruth b12 spray

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MaryRuth Methyl B12 Spray is our go-to advice in relation to sublingual sprays. For those who want a speedy kick of B12 for extra power, this all-natural B12 is the way in which to go.

8. Natrol Vitamin B12

natrol b12

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Natrol’s Vitamin B12 complement is a excessive dosage, fast-delivery possibility. Its 5000 mcg of vitamin B12 will quickly elevate your physique’s circulating ranges of vitamin B12. It’s good for a fast increase in B12, however is much less well-suited for extended use. 

9. Jarrow Formulation Methylcobalamin

jarrow b12

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Jarrow Formulation provides its vitamin B12 in an artificially-sweetened lozenge kind, which you maintain in your mouth like laborious sweet whereas it dissolves.

The dosage could be very excessive, at 5000 mcg per lozenge, so solely use this product if you’re positive that you just want a hue dose of vitamin B12.

10. Cymbiotika B12 + B6

cymbiotika b12 spray

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Cybiotika makes a stable sublingual spray that delivers each B12 and B6, although the inclusion of B6 makes it a bit much less versatile than MaryRuth’s B12 spray.

Class winners

Greatest vitamin B12 total: Stay Aware B12

Stay Aware B12 has a brilliant excessive dosage and an extremely pure formulation. The liquid formulation makes it simple to include into protein shakes and inexperienced drinks, and the citrus taste makes it simple to take by itself, too. Simply one of the best all-around B12 complement available on the market.

Greatest vitamin B12 for power: Twinlab B12 Dots

For those who want power quick, Twinlab B12 Dots are the way in which to go. One dot held beneath your tongue delivers a speedy surge of B12 to your bloodstream, serving to to quickly heighten your power ranges.

Greatest vitamin B12 for vegans: Stay Aware B12

Stay Aware B12 is a liquid-based B12 complement that’s vegan-friendly, tastes nice, and straightforward to make use of, making it the clear winner for vegans wanting to make sure their B12 ranges keep within the optimum vary. 

Greatest vitamin B12 for anxiousness: Nature Made B12 Timed Launch

Deficiencies in B12 and different B-complex nutritional vitamins are recognized to be related to anxiousness, melancholy, and different temper disturbances. Nature Made’s time launch complement is a good possibility for sustaining a steady temper all through the day. 

Greatest vitamin B12 for seniors: Nature Made B12 Timed Launch

Seniors are sometimes poor in vitamin B12, and supplementing with a formulation that provides you a long-lasting increase to your B12 ranges is a good way to maintain greater B12 all day. That’s why we suggest the time launch formulation from Nature Made. 

Greatest vitamin B12 for exercise efficiency: Twinlab B12 Dots

The energy-boosting properties of vitamin B12 make it a very good possibility for elevating your alertness and power ranges earlier than a exercise. Our favourite complement for this goal is Twinlab B12 Dots, due to its speedy under-the-tongue B12 supply mechanism.

Who can buy vitamin B12?

Vitamin B12 could be difficult to get in your weight loss program, particularly when you’ve got any dietary restrictions: it’s present in respectable quantities in just some meals, which embrace beef, eggs, hen, and dairy. The relative rarity of B12 means the next teams of persons are particularly well-suited for a B12 complement:

Vegans and vegetarians. For the reason that richest sources of pure B12 are all in animal merchandise, a B12 complement is a downright necessity for vegetarians and vegans.

Certainly, analysis persistently demonstrates that vegans and vegetarians who don’t complement with B12 are sometimes poor (1, 2).

Pregnant and nursing ladies. B12 is a typical ingredient in prenatal nutritional vitamins due to the advantages of ample B12 consumption in your child.

Younger youngsters. Most of the identical advantages of B12 for infants carry over to younger youngsters: B12 can also be a key ingredient in any high-quality multivitamin for youths as a consequence of its significance for cognitive improvement. 

Older adults. B12 has been the main focus of analysis into stopping or slowing cognitive decline in older adults, and B12 deficiency is sort of widespread amongst older adults, probably as a consequence of decreased bioavailability of B12 as you become old. For seniors, a B12 complement is an effective addition to your supplementation routine. 

Individuals who have had weight reduction surgical procedure. Bariatric surgical procedure can hamper your capability to soak up micronutrients out of your weight loss program, particularly B12. A complement is a good concept for individuals who’ve had surgical procedure to shed pounds.

How we ranked

Given the dietary significance of vitamin B12, our rankings had been strongly knowledgeable by the dosages and complement varieties utilized by medical trials and scientific experiments on vitamin B12.

We used the next evidence-based tips to tell our rankings: 

Efficient B12 dosageSince analysis has discovered that complement dosages of at the very least 500 to 1000 mcg of B12 are optimum for restoring B12 ranges again to regular, we eradicated dietary supplements that had a decrease dosage than this from consideration.

Deal with B12, not simply B-vitamins typically. B12 has some distinctive properties that set it other than the opposite B nutritional vitamins, so we didn’t rank merchandise that didn’t put B12 on the heart of their formulation, like 365 B-Complicated or Thorne Analysis Fundamental B Complicated.

Environment friendly supply mechanismCapsule primarily based dietary supplements had a transparent benefit, as a consequence of their capability to ship a exact dosage each time.

Nonetheless, not everybody is ready to swallow capsules—particularly older adults, who’re disproportionately represented amongst individuals who have low ranges of B12.

So, we additionally analyzed the 2 competing types of supply for B12: gummies and liquid dietary supplements.

Liquid dietary supplements could be useful if you happen to already make a protein shake or inexperienced drink, however they’ve the drawback of not being notably simple to get a dependable dosage.

All-natural components and no fillers. No gummy merchandise made the minimize, since even one of the best choices had been too bloated with synthetic flavors, colours, and binders. 

Clear complement designWe utilized the identical strict requirements of purity and clear complement design to the liquid and capsule primarily based dietary supplements as effectively, rewarding merchandise that saved pointless components to a minimal.

After sorting the remaining merchandise in accordance with high quality, we had our remaining rankings: one of the best B12 dietary supplements which are obtainable available on the market.


Vitamin B12 is important for an enormous variety of bodily features and might solely be present in animal sources. Tlisted here are no plant-based sources of vitamin B12, aside from meals which are fortified with added B12 (3).

Decrease ranges of vitamin B12 may cause anemia and fatigue, so it’s essential to maintain excessive ranges of this vitamin.

B12 may give you extra power. B12 can also be usually used as an power complement, which is why it’s included in many alternative power drinks (4).

An absence of vitamin B12 may cause weak point, dizziness, pale pores and skin, and constipation. These issues are widespread amongst individuals in teams with B12 deficiency, like older adults, vegetarians, and vegans (5). 

Vitamin B12 deficiency is a number one reason behind anemia. An absence of vitamin B12 can restrict your ranges of purple blood cells which provide oxygen to your muscle mass. It will manifest as weak point, fatigue, and poor efficiency throughout train (6).

The prevalence of vitamin B12 deficiency could be very excessive. Shut to 6 % of older adults are B12 clinically poor, and an extra 20% of individuals have “marginal” B12 ranges, which means they’re proper on the sting of low vitamin B12 (7).

B12 dietary supplements can repair B12 deficiency, however it may well take as much as six months. That’s in accordance with analysis printed within the New England Journal of Medication, which adopted individuals with B12 deficiency after they began taking a B12 complement (8).

Low ranges of vitamin B12 could also be implicated within the improvement of cognitive decline. One examine recognized low B12 as a major threat issue for Alzheimer’s illness and dementia (9).

The researchers discovered that low ranges of vitamin B12 elevated Alzheimer’s illness by 4.5-fold.

B12 deficiency is related to melancholy. When in comparison with wholesome topics, individuals with melancholy usually tend to have decrease B12 ranges, in accordance with a examine in Rotterdam (10).

Cardiovascular well being is intently related to vitamin B12. A examine printed in Circulation confirmed that greater blood ranges of vitamin B12 was protecting in opposition to heart problems (11).

Vitamin B12 is important for kids and girls who’re pregnant. Whereas folate will get loads of the eye throughout being pregnant, B12 issues too.

A working group from the World Well being Group stories that deficiencies in B12 throughout being pregnant enhance the chance of neural tube defects, a critical start defect (12).

Some analysis additionally helps an affiliation between low maternal ranges of B12 and different start defects too, however the proof will not be as sturdy.

The significance of B12 for well being doesn’t finish after start. Youngsters who’re poor in vitamin B12 undergo developmental delays, and will not ever absolutely restoration.

Amongst schoolchildren, the working group famous that decrease ranges of B12 correlated with worse grades and decrease scores on exams of cognitive capability.

Weight reduction surgical procedure may cause vitamin B12 deficiency. Getting bariatric surgical procedure, like a lap band or gastric bypass, could be a life-changing process for people who find themselves very overweight. 

Nonetheless, one of many surprising unintended effects of those procedures could be B12 deficiency, which could be handled with supplementation (13).

Unwanted effects

Whereas short-term use of vitamin B12 has no speedy unintended effects, even at very excessive doses, taking excessive doses over a protracted time frame does appear to be linked to an elevated threat of lung most cancers, however solely in males.

Lengthy-term B12 use in people who smoke may enhance lung most cancers threat. A examine from the Ohio State College discovered that males taking excessive doses of vitamin B12 had two to 4 instances the incidence of lung most cancers in comparison with males who didn’t take excessive doses of B12 (14).

This threat must be weighed in opposition to the advantages of B12 supplementation and the dangers of B12 deficiency.

Really useful dosage

B12 supplementation has fairly agency suggestions on dosage for restoring correct B12 ranges.

Purpose for 500 to 1000 mcg per day to deal with B12 deficiency. This quantity comes from a examine that examined doses of two.5 to 1000 micrograms per day of vitamin B12 over the course of a number of weeks to see which doses elicited essentially the most speedy restoration of B12 ranges (15).

Later, you’ll be able to decrease your consumption to keep up your ranges (for instance, throughout being pregnant you want a a lot smaller minimal of 2-2.5 mcg per day (16) if you’re not already poor).


Q: What meals are excessive in vitamin B12? 

A: The listing of meals which are excessive in B12 is surprisingly quick. Beef, salmon and different fish, milk, cheese and different dairy merchandise, and eggs kind of spherical out the numerous sources of pure B12.

Whereas different meals like breakfast cereals are sometimes listed as being excessive in vitamin B12, these meals are fortified with supplemental vitamin B12.

Q: Is it okay to take B12 as a vitamin complement? 

A: Sure, vitamin B12 is extraordinarily secure. No important adversarial results have been related to acute consumption of vitamin B12, in accordance with the Nationwide Institute of Well being’s Workplace of Dietary Dietary supplements (17).

As famous within the unintended effects part of this text, one examine discovered an affiliation between long-term use of vitamin B12 and an elevated threat of lung most cancers, although extra analysis is required to duplicate this discovering.

Individuals who smoke or who’re in any other case at excessive threat for lung most cancers might wish to speak to their physician earlier than taking a vitamin B12 complement long-term, however other than this, it’s okay to take a B12 complement.

Q: What’s cobalamin? 

A: Cobalamin is one other identify for vitamin B12. The phrases are interchangeable, so vitamin B12 means the identical factor as cobalamin. The precise identify comes from the truth that the vitamin B12 molecule has an ion of cobalt at its core.

There’s a little bit of confusion concerning B12 and lots of the different B nutritional vitamins, as they usually have different names (folate, for instance, is similar factor as vitamin B9), however so long as you recognize that they’re one and the identical, it shouldn’t trigger you any hassle.

Q: What does B12 do throughout being pregnant? 

A: Even in adults, vitamin B12 is thought to be vital for correct functioning of the central nervous system. When you recognize this, it shouldn’t be shocking that B12 performs an necessary position within the improvement of your child’s central nervous system and mind.

Neural tube defects, or NTDs, the start defect that’s most strongly related to vitamin B12 deficiency, is a defect of the central nervous system.

Q: Are you able to overdose on vitamin B12?

A: No. B12 is among the most secure vitamin dietary supplements you’ll be able to take. B12 is a water-soluble vitamin, so any extra is solely eradicated in urine.

There have been no documented circumstances of overdose on vitamin B12, and certainly, you’ll discover many examples of dietary supplements that present large doses of vitamin B12 with no obvious ailing impact. 

Q: Is getting a B12 injection higher than taking a complement? 

A: Vitamin B12 injections had been developed for individuals who have poor pure absorption of vitamin B12 from meals and dietary supplements, or who may not reliably be capable to take a B12 complement.

Sure genetic situations can considerably restrict your physique’s capability to soak up vitamin B12, so individuals with these situations usually get a B12 injection as an alternative of taking a complement.

Likewise, some individuals who have gastric bypass surgical procedure or one other bariatric (weight reduction) surgical process might elect to get an occasional B12 injection as an alternative of taking a complement.

On steadiness, although, most individuals are higher off with a complement if they’re able to taking them: dietary supplements are cheaper and far simpler to get.

Q: Are you able to get B12 from greens? 

A: No, there are not any plant-based sources of B12, which is why vegans are at a excessive threat for vitamin B12 deficiency. The one naturally occurring sources of B12 are literally micro organism, that are consumed after which reside as a part of the probiotic flora inside ruminants like cows.

These micro organism proceed producing B12, which progressively accumulates in animal tissue. That’s why the one sources of it are animal-derived meals like dairy, eggs, and meat.

If you’re a vegan, vegetarian, or just don’t eat a lot in the way in which of meat, a B12 complement is an especially good funding in your well being. 

Q: What are the signs of B12 deficiency? 

A: Vitamin B12 deficiency can manifest as tingling, pins and needles sensations, fatigue, continuous tiredness, and pale pores and skin.

Not all the signs are simply observable bodily signs, although. B12 deficiency can even manifest as temper modifications, melancholy, forgetfulness, and different reminiscence issues.

You could really feel as if you might be in a relentless “psychological fog” for no obvious purpose. In case you have these signs, it’s price getting your vitamin B12 ranges checked.

It’s notably necessary to take action in case your weight loss program is fairly wholesome—there could also be an underlying medical trigger for B12 deficiency, like celiac illness and different gastrointestinal issues. 

Q: Are you able to get vitamin B12 naturally? 

A: Sure, however solely from animal meals. The one pure supply of vitamin B12 is from meals like beef, eggs, dairy, and fish.

Whereas crops are nice sources of many different nutritional vitamins and minerals, you gained’t be capable to get even hint quantities of pure vitamin B12 from any plant primarily based meals.

Some meals—notably breads, breakfast cereals, and rice—are sometimes fortified with vitamin B12, so these meals could make appearances on lists of prime sources of vitamin B12, however these are usually not naturally occurring sources of B12.

Associated articles


Vitamin B12 is a crucial nutrient that performs a protecting and preventative position in a number of power ailments, together with Alzheimer’s illness and melancholy.

Vitamin B12 deficiency is quite common; as much as 1 / 4 of older adults have or are at excessive threat for B12 deficiency. A deficiency in vitamin B12 could be fastened with a number of weeks of supplementation at 500 to 1000 micrograms per day, and a decrease dose later to keep up ample ranges of B12 within the physique.

Males, particularly males who smoke, ought to be hesitant to take excessive doses of B12 for lengthy intervals, however the dangers of B12 deficiency should be thought of as effectively.

For BodyNutrition’s #1 vitamin B12 advice, click on right here.

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