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Rating the very best glucosamine dietary supplements of 2022

Glucosamine performs an essential function in preserving joint well being. Glucosamine reduces joint irritation and ache from arthritis, and should assist rebuild broken cartilage and gradual the progressive lack of joint house that happens within the illness.

Many individuals discover that glucosamine is useful for different kinds of joint ache as nicely, akin to sports activities accidents.

Want a glucosamine complement to alleviate your joint ache? Don’t fear, our analysis staff has you coated.

Listed here are the very best glucosamine dietary supplements obtainable proper now.

Why You Ought to Belief Us

    Our advisory panel and our analysis staff rank the very best well being merchandise and dietary supplements primarily based on efficiency, label accuracy, and the efficacy of the elements within the merchandise.


Final up to date: September 2, 2022
Glucosamine dietary supplements thought-about: 25
Hours of analysis: 37
Consultants reviewed: 8
Scientific papers referenced: 12


Finest General

1. Dwell Aware MoveWell Glucosamine

  • Is a simple decide for joint ache
  • Fights irritation, scale back ache, and encourage therapeutic in connective tissue
  • Promotes mobility and suppleness by serving to direct collagen to the joints
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Finest with hyaluronic acid

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2. Important Parts Glucosamine Chondroitin

  • Helps to scale back joint irritation and enhance the formation of recent cartilage
  • Comes with elements that fight soreness and discomfort to advertise higher mobility
  • Improves long run well being for joints
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Finest with MSM

kirkland glucosamien msm

3. Kirkland Signature Glucosamine With MSM

  • Gives easy and environment friendly dietary supplements that deal with your fundamental wants
  • 750 mg of glucosamine in every pill
  • Has a robust anti-inflammatory impact
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schiff glucosamien
  • Delivers 1000 mg of glucosamine hydrochloride per pill
  • Helps and promote joint well being
  • Comprises hyaluronic acid that help cartilage regeneration properties of glucosamine
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Finest for irritation

71PhY3qd9tL. AC SL1200

5. Phytochoice Glucosamine Chondroitin

  • It delivers a steadiness of varied elements to assist with joint ache
  • Every pill incorporates solely 500 mg of glucosamine
  • Strengthens cartilage
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6. Made in Utah Glucosamine Chondroitin Turmeric MSM

  • A barely greater high quality complement with this joint assist product
  • 500 mg of glucosamine per pill
  • Has an anti-inflammatory and ache relieving energy within the complement
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7. Zenwise Superior Energy Joint Assist

  • Finest relating to all-around joint regeneration
  • Promotes higher joint mobility for individuals who have an energetic way of life
  • Advance system that promote energy and suppleness for the joints
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71dOUGHfaAL. AC SL1500

8. USA Nutra Most Energy Glucosamine Chondroitin Turmeric MSM

  • Multi-ingredient complement centered on joint well being
  • 500 mg of glucosamine per pill
  • Helps Irritation
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9. Physician’s Finest Glucosamine Chondroitin MSM

  • Delivers 1500 mg of glucosamine
  • Helps and helps joints and maintains wholesome pores and skin, nails, and hair
  • Gluten free, Soy free, and Non-GMO
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10. Vitabreeze Glucosamine Chondroitin MSM & Turmeric

  • Multi-ingredient joint assist complement
  • Vegetarian Complement that’s Non-GMO, gluten free and soy free
  • Very straightforward to swallow capsules
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11. BlueBonnet Glucosamine Chondroitin Plus MSM

  • Has high-quality and high-purity dietary supplements
  • Low glucosamine content material per pill
  • Soy-free, gluten-free and dairy-free
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1. Dwell Aware MoveWell Glucosamine

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MoveWell helps and protects your joints by sustaining cartilage, lubricating joints, and improve glutathione manufacturing to struggle irritation.

It accomplishes this via a number of clinically backed elements, together with 600mg of chondroitin, 600mg of MSM, 1500mg of glucosamine, 100mg of AprèsFlex® Boswellia, 100mg of curcumin and 100mg of hyaluronic acid per serving.

MoveWell is freed from inflammatory brokers, together with gluten, soy, dairy, and sugar. Additionally it is manufactured in a GMP-certified facility within the USA.

For the best possible joint assist system, MoveWell glucosamine is the very best on the market.

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2. Important Parts Glucosamine Chondroitin

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Important Parts Glucosamine Chondroitin helps to scale back joint irritation and enhance the formation of recent cartilage.

It combines hyaluronic acid, curcumin and MSM with glucosamine and chondroitin to offer among the finest joint reduction available on the market.

Made within the USA and third celebration examined, it’s a superb choice.

3. Kirkland Signature Glucosamine

kirkland glucosamine

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Kirkland Signature offers a strong dosage of glucosamine per pill, and contains MSM as nicely, one other fashionable joint complement that fights irritation and ache.

The capsules have a bit extra binders and fillers than you’ll discover in our prime picks, however the dosage nonetheless makes it a strong decide.

4. Made in Utah Glucosamine

made in utah glucosamine

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Made in Utah has a strong 500 mg of glucosamine per pill, together with chondroitin, turmeric, and MSM plus just a few much less widespread extras. Boswellia extract, quercetin, and methionine all add to its pain-relieving energy.

5. Schiff Glucosamine

schiff glucosamien

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Schiff’s glucosamine formulation delivers 1000 mg of glucosamine hydrochloride per pill, together with 1.6 mg of hyaluronic acid, which assists with cartilage regeneration.

The excessive dose is nice, however purists received’t just like the components, emulsifiers, and coloring brokers included within the capsule.

6. Zenwise Joint Assist

zenwise joint support

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Zenwise is among the many finest relating to all-around joint regeneration. Its glucosamine content material (500 mg) is center of the highway, however you’ll additionally discover the natural extracts like boswellia and curcumin, which will be powerful to seek out within the competitors.

7. Phytochoice Glucosamine Chondroitin

phytochoice glucosamine

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Phytochoice delivers a steadiness of glucosamine, chondroitin, quercetin, turmeric, and boswellia extract, so it’s a fairly versatile choice. Nevertheless, the uncooked dosage of glucosamine shouldn’t be pretty much as good, which hurts its place within the rankings a bit. 

8. USA Nutra Most Energy Glucosamine

71dOUGHfaAL. AC SL1500

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USA Nutra’s tackle glucosamine is fairly good, with 500 mg of glucosamine per pill, in addition to the namesake extras and quercetin and methionine for good measure.

The dearth of additional filler compound is interesting to individuals who need to preserve the components of their complement to a minimal.

9. Physician’s Finest Glucosamine Chondroitin MSM

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Physician’s Finest makes a glucosamine complement filled with glucosamine, chondroitin, and a specialised type of MSM. The one draw back? The per-capsule dosage shouldn’t be so scorching, touchdown it additional down within the rankings.

10. BlueBonnet Glucosamine Chondroitin

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BlueBonnet delivers a easy, efficient glucosamine complement whose solely weak point is a fairly low dose per capsule. The complement design is nice, but it surely simply doesn’t match as much as the competitors relating to dosage.

Class winners

Finest glucosamine general: Dwell Aware MoveWell Glucosamine

MoveWell contains glucosamine alongside an astounding 5 different biologically energetic compounds to struggle irritation, scale back ache, and encourage therapeutic in connective tissue. Because of this breadth of elements, it’s our prime advice.

Finest glucosamine for irritation: Important Parts Glucosamine Chondroitin

Important Parts contains a number of all-natural elements to help with glucosamine’s anti-inflammatory properties. These embrace chondroitin, hyaluronic acid,  and boswellia extract—all of that are nice for reducing again on irritation in your physique.

Finest glucosamine for joint ache: Dwell Aware MoveWell Glucosamine

With joint-nourishing compounds like hyaluronic acid and chondroitin, plus boswellia and curcumin to chop down on irritation, MoveWell is a simple decide for joint ache. 

Finest glucosamine with MSM: Kirkland Signature Glucosamine MSM

If you wish to mix the cartilage-soothing results of glucosamine with the highly effective anti-inflammatory results of MSM, Kirkland is the best way to go. With 750 mg of every, it’s our prime decide for MSM/glucosamine combos. 

Finest glucosamine for knees: Dwell Aware MoveWell Glucosamine

The knee is among the most typical places of arthritis and harm, because of the excessive forces it must bear throughout strolling and different actions. MoveWell is a good selection for folks with knee ache, as a result of it incorporates compounds that fight irritation that happens in response to broken tissue within the knees, and it contains compounds that encourage therapeutic of connective tissue as nicely. 

Finest glucosamine with hyaluronic acid: Dwell Aware MoveWell Glucosamine

Dwell Aware delivers glucosamine alongside 100 mg of hyaluronic acid, which is famend for its capacity to lubricate joint surfaces. The centered formulation of this complement makes it nice for individuals who need to make the most of hyaluronic acid’s mobility-enhancing properties. 

Who should purchase glucosamine?

Glucosamine is among the hottest and only joint dietary supplements for lowering irritation, treating joint ache, and slowing down or doubtlessly even reversing harm to cartilage. It’s an amazing complement for:

Folks with painful knees, hips, or different joints. Glucosamine can’t work miracles, however many individuals discover that it considerably reduces joint ache, and scientific analysis backs up its potential to decelerate goal markers of joint harm.

Folks with osteoarthritis. Many of the analysis supporting using glucosamine focuses on osteoarthritis, which causes harm, degeneration, and irritation, suggesting this can be a nice use-case for glucosamine.  

Folks with sports activities accidents to their joints. Glucosamine can do extra than simply assist arthritis: some analysis signifies it’s a helpful strategy to scale back ache from sports activities accidents, like outdated knee or ankle sprains that by no means totally healed.

How we ranked

Since glucosamine is so well-studied within the scientific literature, we used the very best scientific analysis to information our choice of glucosamine dietary supplements, primarily based on the next standards: 

Efficient dosageWe appeared for dosages and formulations that lined up nicely with scientific research —that meant dietary supplements that make it straightforward to take what seems to be the optimum dosage for glucosamine, which is at the least 1500 mg of glucosamine per day.

A concentrate on delivering pure glucosamine. Not like our rankings of general-purpose joint dietary supplements, we put much less emphasis on the inclusion of different doubtlessly biologically energetic compounds like MSM or hyaluronic acid when evaluating the standard of a glucosamine complement.

Whereas extra elements had been a small perk that boosted the scores of some glucosamine dietary supplements in our rankings, our main focus was dosage and purity.

No binders, fillers, or synthetic components. We dropped dietary supplements from consideration in the event that they contained an excessive amount of in the best way of binders and fillers.

Since glucosamine is already derived from animal merchandise (shellfish, normally), it didn’t matter to our analysis staff whether or not the complement was delivered in a cellulose or gelatin capsule.

The highest performers had been merchandise that successfully delivered a excessive dose of glucosamine whereas protecting further elements to a minimal.

If you’re in search of a glucosamine complement that gives the identical advantages seen in essentially the most profitable scientific analysis, you’ll discover it in our rankings.


Glucosamine helps scale back irritation and joint ache. It fights ache by by encouraging cartilage to soak up extra water, protecting the cartilage hydrated (1,2).

Glucosamine can also improve the synthesis of cartilage tissue. Analysis on older adults with arthritis signifies that glucosamine can gradual or halt the development of joint harm in arthritis (3,4).

Glucosamine upregulates synthesis of the constructing blocks of cartilage. In accordance with a research printed by researchers in Italy, glucosamine sulfate will increase the synthesis of a kind of protein referred to as proteoglycan, which make up a major quantity of the mass in cartilage (5).

Glucosamine may assist scale back ache from outdated sports activities accidents. A research on folks with injury-related, non-arthritic knee ache skilled important enhancements in ache after taking 2000 mg of glucosamine for twelve weeks (6).

Glucosamine works higher for joint ache than again ache. In distinction to the above outcomes on knee and hip ache, analysis from Norway suggests glucosamine shouldn’t be as useful when you could have continual low again ache (7).

Negative effects

Analysis reveals glucosamine is secure and well-tolerated by virtually everybody. Scientific trials haven’t discovered any important distinction within the fee of unwanted effects in glucosamine versus placebo.

Glucosamine is derived from shellfish, so it may set off shellfish allergic reactions. The one potential antagonistic impact to concentrate on is the truth that glucosamine is derived from marine shells, so anybody with a extreme shellfish allergy ought to keep away from glucosamine dietary supplements.

Advisable dosage

Finest outcomes come from round 1500 mg per day. That quantity comes from a research that examined doses from 750 to 3000 mg per day (8).

Above 1500 mg per day your physique can’t take in any extra glucosamine. Increased doses are nonetheless secure, however don’t present any extra advantages by way of bioavailability.


Q: Why would you’re taking glucosamine?

A: Glucosamine is hottest as a complement for joint ache that’s linked to osteoarthritis, and that is the appliance that’s most well-supported by scientific analysis.

Nevertheless, it’s additionally logical to take glucosamine for different joint ache, like knee ache from an acute sports activities harm, or ache and irritation from outdated joint accidents that by no means totally went away.

Q: Is glucosamine good on your joints?

A: Glucosamine has been studied closely as a approach to enhance joint well being and gradual and even doubtlessly reverse the degenerative progress of osteoarthritis, the place cartilage is progressively broken and infected over time, resulting in ache and incapacity.

Whereas glucosamine can’t work miracles, it does lower down on among the ache and limitations to your regular every day routine that may be attributable to joint harm and illness.

Q: Do any joint dietary supplements actually work?

A: The very best scientific analysis helps small however important advantages from joint dietary supplements primarily based on glucosamine, chondroitin, and MSM as nicely.

Quercetin is one other complement for joint well being that has some analysis supporting it, as does fish oil.

In each of those instances, these joint complement elements are thought to exert antioxidant and anti inflammatory results, reducing down on the cellular-level aggravation within the joint.

Q: Is glucosamine in meals?

A: Glucosamine shouldn’t be present in any meals in any important quantity.

It’s a naturally-occurring compound, however you couldn’t get a dose anyplace close to what’s utilized in scientific supplementation research even in a really nutritious diet.

The one strategy to get glucosamine in any important quantity is to make use of a glucosamine complement.

Q: Is there anybody who shouldn’t take glucosamine?

A: Since glucosamine is derived from shellfish, you shouldn’t take glucosamine if you understand you could have a shellfish allergy.

Q: Is glucosamine helpful alongside MSM?

A: Glucosamine is assumed to boost the organic efficacy of methylsulfonylmethane, or MSM, which is one other widespread complement used for joint ache.

You’ll usually discover each glucosamine and MSM used as elements in joint dietary supplements, and a few analysis has efficiently examined the efficacy of each together (9,10).

Q: What’s glucosamine chondroitin?

A: Glucosamine chondroitin is a time period utilized to joint dietary supplements that embrace each glucosamine and chondroitin, which is a chemically distinct molecule.

Chondroitin is a direct structural element of cartilage, and is assumed to assist increase the synthesis of recent cartilage in broken joints.

Glucosamine additionally helps assist joint well being, and most multi-ingredient joint dietary supplements financial institution on each glucosamine and chondroitin being more practical together than alone.

Q: How does glucosamine work?

A: Glucosamine is a precursor to a kind of compound referred to as glycosaminoglycan, which in flip is used each as a constructing block for cartilage, and as a lubricant and shock absorber inside joints.

Analysis on cartilage tissue means that glucosamine will increase cartilage water content material and will increase cartilage protein synthesis, plus boosts the provide of lubricating and shock-absorbing fluids within the joint house.

Q: How lengthy does it take for glucosamine to work?

A: Most analysis on using glucosamine is at the least just a few months in size, so you must attempt glucosamine for at the least this lengthy to see if it really works.

One research on utilizing glucosamine to deal with long-term knee ache explicitly examined the time-course of glucosamine’s results and located that a lot of the advantages attributable to glucosamine had appeared after eight weeks of use (11).

So, should you’ve solely been utilizing glucosamine for a few weeks, you could not have been utilizing it lengthy sufficient to get the total impact of the complement.

Q: What’s the finest time to take glucosamine?

A: The timing of while you take glucosamine shouldn’t be significantly essential, as a result of it’s pretty long-lasting in your physique.

Nevertheless, you do need to take it each single day at roughly the identical time to get optimum results.

That’s what the pharmacological analysis helps, and is the protocol utilized by essentially the most profitable analysis research on utilizing glucosamine.

Q: How lengthy does glucosamine keep in your system?

A: Scientific analysis has estimated the elimination half-life of glucosamine at about 15 hours, that means that after taking a full dose of glucosamine, half of it has been eradicated out of your physique 15 hours later (12).

Which means after you cease taking glucosamine, it’ll take just a few days for it to get completely eradicated out of your system.

Because of this comparatively lengthy elimination half life, you don’t must take glucosamine any extra usually than as soon as day by day.

Q: What’s glucosamine comprised of?

A: Glucosamine is normally made by taking shells from shellfish (like clams or oysters) and breaking down the molecules that make up their shells.

It’s a simple, cheap, and efficient strategy to purchase a considerable amount of glucosamine.

This course of can also be why it’s endorsed to take glucosamine when you have a shellfish allergy—it’s seemingly that the allergens current in shellfish are additionally current in glucosamine in hint quantities.

Associated articles


Glucosamine is a complement whose efficacy has been examined by a number of massive scientific trials and has important advantages on joint ache.

Glucosamine seems to be only at stopping the lack of cartilage in your joints that comes from osteoarthritis, and in addition appears to be efficient in lots of (however not all) research inspecting ache and day-to-day operate.

This means that glucosamine is finest used early on to decelerate the development of arthritis, when your ache continues to be gentle.

Glucosamine could be very well-tolerated, that means that you just don’t want to fret about unwanted effects, and the optimum dosage for finest outcomes seems to be round 1500 mg per day.

For BodyNutrition’s #1 glucosamine advice, click on right here.

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